产品货号:
Z25136
中文名称:
RNF25抗体
英文名称:
Anti-RNF25 Antibody
产品规格:
100μg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-RNF25 Antibody |
指标别名 | Rnf25,E3 ubiquitin protein ligase RNF25,Ring finger protein 25,RING-type E3 ubiquitin transferase Rnf25,RNF 25,RNF-25 |
克隆性 | Polyclonal |
检验物种 | human,mouse |
应用范围 | ELISA,WB |
基因名称 | RNF25 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids near the carboxyl terminus of human RNF25 protein. |
计算分子量 | 51kDa |
成分 | 0.02M Potassium Phosphate,0.15M Sodium Chloride,pH7.2,0.01% (w/v) Sodium Azide |
纯化方式 | This affinity purified antibody is directed against human RNF25 protein.The product was affinity purified from monospecific antiserum by immunoaffinity chromatography.?The antibody also recognizes mouse RNF25 protein.Reactivity against homologues from other sources has not been determined. |
浓度 | 1.1mg/mL by UV absorbance at 280nm |
产品形态 | 溶液 |
保存条件 | Store vial at -20℃ prior to opening.Aliquot contents and freeze at -20℃ or below for extended storage.Avoid cycles of freezing and thawing.Centrifuge product if not completely clear after standing at room temperature.This product is stable for several weeks at 4℃ as an undiluted liquid.Dilute only prior to immediate use.Expiration date is one (1) year from date of opening. |
背景资料 | This antibody is suitable for Cancer,Immunology and Nuclear Signaling research.RING finger protein 25 (RNF25,also named AO7) contains a RING finger domain and is ubiquitously expressed in various tissues.RNF25 was initially identified in a yeast two-hybrid screen of a murine T-cell library by using UbcH5b,an E2 enzyme,as bait.RNF25 has also been shown to act as a putative E3 ligase,at least in vitro.RNF25 localizes predominantly in the nucleus and supports the transcriptional activity of NF-kB by interacting with p65 in vivo upon stimulation with TNF.yeast two-hybrid data also suggest that RNF25 interacts with a number of other molecules which may be potential ubiquitin ligase substrates.Among these are molecules that have critical roles in signal transduction and in regulation of translation (personal communication,Allan Weissman,CCR-NCI,Bethesda,MD). |
Uniprot ID | Q96BH1 |
基因名全称 | E3 ubiquitin-protein ligase RNF25 |
推荐稀释比 | ELISA:1:10,000 - 1:40,000 IP:1mg WB:1:200 - 1:2,000 |
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