产品货号：
Z25123
中文名称：
RNF43抗体
英文名称：
Anti-RNF43 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-RNF43 Antibody |
| 指标别名 | ring finger protein 43;RNF124;SSPCS;URCC;RNF43 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,ELISA |
| 基因名称 | RNF43 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human RNF43 recombinant protein (Position:G24-Y197). |
| 实际分子量 | 86KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | RNF43 is a HAP95 (AKAP8L) binding ubiquitin ligase that promotes cell growth and is upregulated in colon cancer.The protein encoded by this gene is a RING-type E3 ubiquitin ligase and is predicted to contain a transmembrane domain,a protease-associated domain,an ectodomain,and a cytoplasmic RING domain.This protein is thought to negatively regulate Wnt signaling,and expression of this gene results in an increase in ubiquitination of frizzled receptors,an alteration in their subcellular distribution,resulting in reduced surface levels of these receptors.Mutations in this gene have been reported in multiple tumor cells,including colorectal and endometrial cancers.Alternative splicing results in multiple transcript variants encoding different isoforms. |
| Uniprot ID | Q68DV7 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 (ELISA)： 1:100～1000 |
相关搜索：RNF43抗体，RNF43多抗，Anti-RNF43 Antibody