产品货号：
Z25081
中文名称：
RBX1抗体
英文名称：
Anti-RBX1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-RBX1 Antibody |
| 指标别名 | Protein ZYP;RBX1;Regulator of cullins 1;ring box 1;RING box protein 1;RING finger protein 75;RNF75;ROC1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,ICC/IF,FCM |
| 基因名称 | RBX1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of human ROC1 (76-108aa NHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH),identical to the related mouse sequence. |
| 实际分子量 | 12KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | RING-box protein 1,also known as ROC1,is a protein that in humans is encoded by the RBX1 gene.This gene is mapped to chromosome 22q13.2 based on an alignment of the RBX1 sequence with the genomic sequence.ROC1 is recruited by cullin-1 to form a quaternary SCF (HOS)-ROC1 holoenzyme (with SKP1 and the BTRCP homolog HOS).SCF (HOS)-ROC1 binds IKK-beta-phosphorylated I-kappa-B-alpha and catalyzes its ubiquitination in the presence of ubiquitin,E1,and CDC34.Conclusively,ROC1 plays a unique role in the ubiquitination reaction by heterodimerizing with cullin-1 to catalyze ubiquitin polymerization. |
| Uniprot ID | P62877 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | ring-box 1,E3 ubiquitin protein ligase |
| 蛋白名全称 | E3 ubiquitin-protein ligase RBX1 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Flow cytometry (FCM) 1～3μg/1×106 cells Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 |
相关搜索：RBX1抗体，RBX1多抗，Anti-RBX1 Antibody