RAIDD/CRADD抗体

产品货号：

Z24991

中文名称：

RAIDD/CRADD抗体

英文名称：

Anti-RAIDD/CRADD Antibody

产品规格：

0.1mg

发货周期：

1～3天

产品价格：

询价

抗体名称	Anti-RAIDD/CRADD Antibody
指标别名	CRADD;RAIDD
克隆性	Polyclonal
检验物种	human
应用范围	ELISA,WB,ICC,IF
基因名称	CRADD
抗体来源	Rabbit
抗体类型	IgG
免疫原	RAIDD antibody was raised against a 19 amino acid peptide near the center of human RAIDD.The immunogen is located within amino acids 90 - 140 of RAIDD.
计算分子量	23kDa
成分	RAIDD Antibody is supplied in PBS containing 0.02% sodium azide.
纯化方式	RAIDD Antibody is affinity chromatography purified via peptide column.
浓度	1mg/mL
产品形态	溶液
保存条件	4℃可保存3个月，-20℃可保存1年。
背景资料	Apoptosis,or programmed cell death,occurs during normal cellular differentiation and development of multicellular organisms.Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain (DD)-containing receptors,TNFR1 and Fas.The death signals are transduced by a group of DD-containing adapter molecules.A novel cell death adapter was recently identified by two independent groups and designated RAIDD (RIP-associated ICH-1/CED-3-homologous protein with DD) and CRADD (caspase and RIP adapter with DD)1,RAIDD contains a DD and a CARD (for caspase recruitment domain) which interact with RIP and caspase,respectively,to transduce death signals1,3.RAIDD is constitutively expressed in many tissues and mediates apoptosis caused by Fas and TNFR-1.
Uniprot ID	P78560
基因名全称	CASP2 and RIPK1 domain containing adaptor with death domain
蛋白名全称	CASP2 and RIPK1 domain containing adaptor with death domain
推荐稀释比	RAIDD antibody can be used for detection of RAIDD by Western blot at 0.5 ～ 1μg/mL.A 22kDa band should be detected.Antibody can also be used for immunocytochemistry starting at 5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples;Immunocytochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested.

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