产品货号：
Z24952
中文名称：
RAP1GAP抗体
英文名称：
Anti-RAP1GAP Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-RAP1GAP Antibody |
| 指标别名 | RAP1GA1;Rap1GAP;Rap1GAP1;RAP1GAPII;RAPGAP |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,ICCIF,FCM,ELISA |
| 基因名称 | RAP1GAP |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human RAP1GAP recombinant protein (Position:D11-L661). |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Rap1 GTPase-activating protein 1 is an enzyme that in humans is encoded by the RAP1GAP gene.This gene encodes a type of GTPase-activating-protein (GAP) that down-regulates the activity of the ras-related RAP1 protein.RAP1 acts as a molecular switch by cycling between an inactive GDP-bound form and an active GTP-bound form.The product of this gene,RAP1GAP,promotes the hydrolysis of bound GTP and hence returns RAP1 to the inactive state whereas other proteins,guanine nucleotide exchange factors (GEFs),act as RAP1 activators by facilitating the conversion of RAP1 from the GDP- to the GTP-bound form.In general,ras subfamily proteins,such as RAP1,play key roles in receptor-linked signaling pathways that control cell growth and differentiation.RAP1 plays a role in diverse processes such as cell proliferation,adhesion,differentiation,and embryogenesis.Alternative splicing results in multiple transcript variants encoding distinct proteins. |
| Uniprot ID | P47736 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P) and ICC. |
| 基因名全称 | RAP1 GTPase activating protein |
| 蛋白名全称 | Rap1 GTPase-activating protein 1 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells ELISA 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
| Gene ID | 5909 |
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