产品货号:
Z24941
中文名称:
RIPK1抗体
英文名称:
Anti-RIPK1 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-RIPK1 Antibody |
指标别名 | Cell death protein RIP;Receptor interacting protein 1;RIP;RIP 1;RIP1;RIPK1;RIPK1-Specific |
克隆性 | Polyclonal |
检验物种 | human |
应用范围 | WB |
基因名称 | RIPK1 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | E.coli-derived human RIP recombinant protein (Position:K316-N671).Human RIP shares 65% amino acid (aa) sequence identity with mouse RIP. |
实际分子量 | 76KD |
成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
纯化方式 | Immunogen affinity purified. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | RIPK1,also known as RIP or RIP1,is an enzyme that in humans is encoded by the RIPK1 gene.It is mapped to 6p25.2.RIPK1 is a key signaling molecule in the programmed necrosis pathway,which plays important roles in development,tissue damage response,and antiviral immunity.RIPK1 is known to have function in a variety of cellular pathways including the NF-κB pathway and programmed necrotic cell death (necroptosis).The kinase domain,while important for necroptotic (programmed necrotic) functions,it appears dispensable for other lethal,as well as pro-survival roles.Also,proteolytic processing of RIPk1,through both caspase-dependent and -independent mechanisms,triggers lethality that is dependent on the generation of one or more specific C-terminal cleavage product(s) of RIPk1 upon stress. |
Uniprot ID | Q13546 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
基因名全称 | receptor (TNFRSF)-interacting serine-threonine kinase 1 |
蛋白名全称 | Receptor-interacting serine/threonine-protein kinase 1 |
推荐稀释比 | Western blot(WB) 1:500~2000 |
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