产品货号：
Z24905
中文名称：
RAF1抗体
英文名称：
Anti-RAF1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-RAF1 Antibody |
| 指标别名 | c Raf;CRAF;NS5;Proto oncogene c RAF;RAF;Raf 1;RAF1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,FCM |
| 基因名称 | RAF1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human Raf1 recombinant protein (Position:Y364-Q451).Human Raf1 shares 98.9% amino acid (aa) sequence identity with both mouse and rat Raf1. |
| 实际分子量 | 73KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | RAF proto-oncogene serine/threonine-protein kinase,also known as proto-oncogene c-RAF or simply c-Raf or even Raf-1,is an enzyme that in humans is encoded by the RAF1 gene.This gene is the cellular homolog of viral raf gene (v-raf).The encoded protein is a MAP kinase kinasekinase (MAP3K),which functions downstream of the Ras family of membrane associated GTPases to which it binds directly.Once activated,the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2,which in turn phosphorylate to activate the serine/threonine specific protein kinases,ERK1 and ERK2.Activated ERKs are pleiotropic effectors of cell physiology and play an important role in the control of gene expression involved in the cell division cycle,apoptosis,cell differentiation and cell migration.Mutations in this gene are associated with Noonan syndrome 5 and LEOPARD syndrome 2. |
| Uniprot ID | P04049 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Flow cytometry (FCM) 1～3μg/1×106 cells |
相关搜索：RAF1抗体，RAF1多抗，Anti-RAF1 Antibody