产品货号：
Z24872
中文名称：
RAD17抗体
英文名称：
Anti-RAD17 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-RAD17 Antibody |
| 指标别名 | CCYC;HRAD17;R24L;RAD17;RAD17 homolog (S.pombe);RAD17SP;RAD24;RF C/activator 1 homolog |
| 克隆性 | Polyclonal |
| 检验物种 | mouse,rat |
| 应用范围 | WB,IHC,FCM,ELISA |
| 基因名称 | Rad17 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived mouse Rad17 recombinant protein (Position:M1-Q267). |
| 实际分子量 | 77KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad17,a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage.This protein shares strong similarity with DNA replication factor C (RFC),and can form a complex with RFCs.This protein binds to chromatin prior to DNA damage and is phosphorylated by the checkpoint kinase ATR following damage.This protein recruits the RAD1-RAD9-HUS1 checkpoint protein complex onto chromatin after DNA damage,which may be required for its phosphorylation.The phosphorylation of this protein is required for the DNA-damage-induced cell cycle G2 arrest,and is thought to be a critical early event during checkpoint signaling in DNA-damaged cells.Multiple alternatively spliced transcript variants of this gene,which encode four distinct protein isoforms,have been reported.Two pseudogenes,located on chromosomes 7 and 13,have been identified. |
| Uniprot ID | Q6NXW6 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot. |
| 基因名全称 | RAD17 checkpoint clamp loader component |
| 蛋白名全称 | Cell cycle checkpoint protein RAD17 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells ELISA 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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