产品货号：
Z24866
中文名称：
RAD18抗体
英文名称：
Anti-RAD18 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-RAD18 Antibody |
| 指标别名 | hHR18;hRAD18;RAD18;RAD18 homolog (S.cerevisiae);RING finger protein 73;RNF73 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,FCM,ELISA |
| 基因名称 | RAD18 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human RAD18 recombinant protein (Position:M1-D408). |
| 实际分子量 | 70KD |
| 成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | E3 ubiquitin-protein ligase RAD18 is an enzyme that in humans is encoded by the RAD18 gene.The protein encoded by this gene is highly similar to S.cerevisiae DNA damage repair protein Rad18.Yeast Rad18 functions through its interaction with Rad6,which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA.Similar to its yeast counterpart,this protein is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif.Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens. |
| Uniprot ID | Q9NS91 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P). |
| 基因名全称 | RAD18 E3 ubiquitin protein ligase |
| 蛋白名全称 | E3 ubiquitin-protein ligase RAD18 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells (ELISA)： 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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