产品货号：
Z24861
中文名称：
PTPN22抗体
英文名称：
Anti-PTPN22 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-PTPN22 Antibody |
| 指标别名 | Lymphoid phosphatase;LYP;LYP1;LYP2;PEP;PTPN22;PTPN8 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC-F,ICC,FCM |
| 基因名称 | PTPN22 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the N-terminus of human PTPN22 (1-42aa MDQREILQKFLDEAQSKKITKEEFANEFLKLKRQSTKYKADK),different from the related mouse sequence by eight amino acids. |
| 实际分子量 | 98KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Protein tyrosine phosphatase,non-receptor type 22 (lymphoid),also known as PTPN22,is a protein that in humans is encoded by the PTPN22 gene.This gene encodes of member of the non-receptor class 4 subfamily of the protein-tyrosine phosphatase family.The encoded protein is a lymphoid-specific intracellular phosphatase that associates with the molecular adapter protein CBL and may be involved in regulating CBL function in the T-cell receptor signaling pathway.Mutations in this gene may be associated with a range of autoimmune disorders including Type 1 Diabetes,rheumatoid arthritis,systemic lupus erythematosus and Graves' disease.Alternatively spliced transcript variants encoding distinct isoforms have been described. |
| Uniprot ID | Q9Y2R2 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | protein tyrosine phosphatase,non-receptor type 22 (lymphoid) |
| 蛋白名全称 | Tyrosine-protein phosphatase non-receptor type 22 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in frozen section (IHC-F) 1:50～400 Immunocytochemistry in fixed cells(ICC) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells |
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