产品货号：
Z24826
中文名称：
PSME1抗体
英文名称：
Anti-PSME1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-PSME1 Antibody |
| 指标别名 | PSME1;IFI5111;Proteasome activator complex subunit 1;11S regulator complex subunit alpha;REG-alpha;Activator of multicatalytic protease subunit 1;Interferon gamma up-regulated I-5111 protein;IGUP I-5111;Proteasome activator 28 subunit alpha;PA28a;PA28alpha |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,ICC/IF,FCM(Intracellular),Direct ELISA |
| 基因名称 | PSME1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human PSME1 recombinant protein (Position:M1-Y249). |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Proteasome activator complex subunit 1 is a protein that in humans is encoded by the PSME1 gene.The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes,a 20S core and a 19S regulator.The 20S core is composed of 4 rings of 28 non-identical subunits;2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits.The 19S regulator is composed of a base,which contains 6 ATPase subunits and 2 non-ATPase subunits,and a lid,which contains up to 10 non-ATPase subunits.Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway.An essential function of a modified proteasome,the immunoproteasome,is the processing of class I MHC peptides.The immunoproteasome contains an alternate regulator,referred to as the 11S regulator or PA28,that replaces the 19S regulator.Three subunits (alpha,beta and gamma) of the 11S regulator have been identified.This gene encodes the alpha subunit of the 11S regulator,one of the two 11S subunits that is induced by gamma-interferon.Three alpha and three beta subunits combine to form a heterohexameric ring.Alternative splicing results in multiple transcript variants. |
| Uniprot ID | Q06323 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot. |
| 基因名全称 | proteasome activator subunit 1 |
| 蛋白名全称 | Proteasome activator complex subunit 1 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 Flow Cytometry(Intracellular) 1～3μg/1×106 cells Direct ELISA 1:100～1000 |
| Gene ID | 5720 |
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