产品货号：
Z24808
中文名称：
PPM2C/PDP1抗体
英文名称：
Anti-PPM2C/PDP1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-PPM2C/PDP1 Antibody |
| 指标别名 | PDH;PDP;PDP 1;PDP1;PDPC;PDPC 1;PPM2C;Protein phosphatase 2C |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,ICC/IF,FCM,ELISA |
| 基因名称 | PDP1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human PDP1/PDP recombinant protein (Position:S37-E537). |
| 实际分子量 | 53～61KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Pyruvate dehydrogenase (E1) is one of the three components (E1,E2,and E3) of the large pyruvate dehydrogenase complex.Pyruvate dehydrogenase kinases catalyze phosphorylation of serine residues of E1 to inactivate the E1 component and inhibit the complex.Pyruvate dehydrogenase phosphatases catalyze the dephosphorylation and activation of the E1 component to reverse the effects of pyruvate dehydrogenase kinases.Pyruvate dehydrogenase phosphatase is a heterodimer consisting of catalytic and regulatory subunits.Two catalytic subunits have been reported;one is predominantly expressed in skeletal muscle and another one is is much more abundant in the liver.The catalytic subunit,encoded by this gene,is the former,and belongs to the protein phosphatase 2C (PP2C) superfamily.Along with the pyruvate dehydrogenase complex and pyruvate dehydrogenase kinases,this enzyme is located in the mitochondrial matrix.Mutation in this gene causes pyruvate dehydrogenase phosphatase deficiency.Multiple alternatively spliced transcript variants encoding different isoforms have been identified. |
| Uniprot ID | Q9P0J1 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot. |
| 基因名全称 | pyruvate dehydrogenase phosphatase catalytic subunit 1 |
| 蛋白名全称 | [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1,mitochondrial |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells ELISA 1:100～1000 |
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