产品货号:
Z24730
中文名称:
PTPN12抗体
英文名称:
Anti-PTPN12 Antibody
产品规格:
100μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-PTPN12 Antibody |
指标别名 | PTPN12;Tyrosine-protein phosphatase non-receptor type 12;EC 3.1.3.48;PTP-PEST;Protein-tyrosine phosphatase G1;PTPG1 |
克隆性 | Polyclonal |
检验物种 | human,mouse |
应用范围 | WB,ELISA |
基因名称 | PTPN12 |
抗体来源 | Rabbit |
抗体类型 | IgG |
计算分子量 | 88KD |
成分 | Liquid form in PBS containing 50% glycerol,and 0.02% sodium azide. |
纯化方式 | PTN12 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | -20℃可保存1年,短期保存或频繁使用请置于4℃,可保存一个月,避免反复冻融。 |
背景资料 | Tyrosine-protein phosphatase non-receptor type 12 is an enzyme that in humans is encoded by the PTPN12 gene.The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family.PTPs are signaling molecules that regulate a variety of cellular processes including cell growth,differentiation,mitotic cycle,and oncogenic transformation.This PTP contains a C-terminal PEST motif,which serves as a protein-protein interaction domain,and may regulate protein intracellular half-life.This PTP was found to bind and dephosphorylate the product of the oncogene c-ABL and thus may play a role in oncogenesis.This PTP was also shown to interact with,and dephosphorylate,various products related to cytoskeletal structure and cell adhesion,such as p130 (Cas),CAKbeta/PTK2B,PSTPIP1,and paxillin.This suggests it has a regulatory role in controlling cell shape and mobility.Alternative splicing results in multiple transcript variants encoding distinct isoforms. |
Uniprot ID | Q05209 |
基因名全称 | Tyrosine-protein phosphatase non-receptor type 12 |
蛋白名全称 | Tyrosine-protein phosphatase non-receptor type 12 |
推荐稀释比 | WB 1:500~2000 ELISA 1:5000~20000 |
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