产品货号:
Z24729
中文名称:
PTPN13抗体
英文名称:
Anti-PTPN13 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-PTPN13 Antibody |
指标别名 | PTPN13;PNP1;PTP1E;PTPL1;Tyrosine-protein phosphatase non-receptor type 13;Fas-associated protein-tyrosine phosphatase 1;FAP-1;PTP-BAS;Protein-tyrosine phosphatase 1E;PTP-E1;hPTPE1;Protein-tyrosine phosphatase PTPL1 |
克隆性 | Polyclonal |
检验物种 | human |
应用范围 | WB,FCM(Intracellular),ELISA |
基因名称 | PTPN13 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | E.coli-derived human PTPN13 recombinant protein (Position:E1795-D2046). |
实际分子量 | 270KD |
成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
纯化方式 | Immunogen affinity purified. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | Tyrosine-protein phosphatase non-receptor type 13 is an enzyme that in humans is encoded by the PTPN13 gene.The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family.PTPs are signaling molecules that regulate a variety of cellular processes including cell growth,differentiation,mitotic cycle,and oncogenic transformation.This PTP is a large intracellular protein.It has a catalytic PTP domain at its C-terminus and two major structural domains:a region with five PDZ domains and a FERM domain that binds to plasma membrane and cytoskeletal elements.This PTP was found to interact with,and dephosphorylate,Fas receptor and IkappaBalpha through the PDZ domains.This suggests it has a role in Fas mediated programmed cell death.This PTP was also shown to interact with GTPase-activating protein,and thus may function as a regulator of Rho signaling pathways.Four alternatively spliced transcript variants,which encode distinct proteins,have been reported. |
Uniprot ID | Q12923 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot. |
基因名全称 | protein tyrosine phosphatase non-receptor type 13 |
蛋白名全称 | Tyrosine-protein phosphatase non-receptor type 13 |
推荐稀释比 | Western blot (WB) 1:500~2000 Flow Cytometry(Intracellular) 1~3μg/1×106 cells ELISA 1:100~1000 |
Gene ID | 5783 |
相关搜索:PTPN13抗体,PTPN13多抗,Anti-PTPN13 Antibody