产品货号:
Z24700
中文名称:
RAB7A抗体
英文名称:
Anti-RAB7A Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
| 抗体名称 | Anti-RAB7A Antibody |
| 指标别名 | Endosome Marker;PRO2706;RAB7;RAB7A;Ras related protein Rab 7a |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,ICC/IF,FCM |
| 基因名称 | RAB7A |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of human RAB7 (157-196aa KEAINVEQAFQTIARNALKQETEVELYNEFPEPIKLDKND),identical to the related mouse sequence,and different from the related rat sequence by one amino acid. |
| 实际分子量 | 23KD |
| 成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Ras-related protein Rab-7a is a protein that in humans is encoded by the RAB7A gene.RAB7A functions as a key regulator in endo-lysosomal trafficking,governs early-to-late endosomal maturation,microtubule minus-end as well as plus-end directed endosomal migration and positions,and endosome-lysosome transport through different protein-protein interaction cascades.Furthermore,RAB7A is involved in regulation of some specialized endosomal membrane trafficking,such as maturation of melanosomes through modulation of SOX10 and the oncogene MYC.Mutations in the lysosomal pathway result in tumor progression in melanoma cells. |
| Uniprot ID | P51149 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | RAB7A,member RAS oncogene family |
| 蛋白名全称 | Ras-related protein Rab-7a |
| 推荐稀释比 | Western blot(WB) 1:500~2000 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50~400 Flow cytometry (FCM) 1~3μg/1×106 cells |
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