产品货号：
Z24674
中文名称：
PPAPDC1B抗体
英文名称：
Anti-PPAPDC1B Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-PPAPDC1B Antibody |
| 指标别名 | DPPL1,HTPAP,DPPL1,Phosphatidate phosphatase PPAPDC1B,Phosphatidic acid phosphatase type 2 domain-containing protein 1B |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | ELISA,WB |
| 基因名称 | PPAPDC1B |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | PPAPDC1B antibody was raised against a 14 amino acid synthetic peptide near the amino terminus of human PPAPDC1B.The immunogen is located within amino acids 30 - 80 of PPAPDC1B. |
| 计算分子量 | 29kDa |
| 成分 | PPAPDC1B Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | PPAPDC1B Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | Phosphatidate phosphatase (PAP) plays important role in lipid-signaling metabolism in eukaryotic cells.Two distinct types of PAP (PAP1 and PAP2) activity have been distinguished by their subcellular localization and differential sensitivity to N-ethylmaleimide (NEM) and Mg2+.A yeast diacylglycerol pyrophosphate (DGPP) phosphatase (DPP1) and mammalian DGPP phosphatase (PAP2) have been identified as Mg2+-independent and NEM-insensitive membrane-associated.PPAPDC1A (also known as DPPL2) and PPAPDC1B (DPPL1) form a novel type of Mg2+-independent and NEM-sensitive mammalian phosphatidate phosphatase showing broad substrate specificity.Knockdown experiments indicated that this protein is involved with multiple cell signaling pathways,including the JAK-Stat3,MAP kinase,and PKC pathways.PPAPDC1B may also potentiate the estrogen receptor pathway by down-regulating DUSP22. |
| Uniprot ID | Q8NEB5 |
| 基因名全称 | Phosphatidic acid phosphatase type 2 domain containing 1B |
| 蛋白名全称 | Phosphatidic acid phosphatase type 2 domain containing 1B |
| 推荐稀释比 | PPAPDC1B antibody can be used for detection of PPAPDC1B by Western blot at 1 ～ 2μg/mL.Antibody validated:Western Blot in mouse samples.All other applications and species not yet tested. |
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