产品货号：
Z24519
中文名称：
PRX5/PRDX5抗体
英文名称：
Anti-PRX5/PRDX5 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-PRX5/PRDX5 Antibody |
| 指标别名 | ACR1;Alu corepressor 1;Antioxidant enzyme B166;AOEB166;AOPP;B166;Liver tissue 2D page spot 71B;Peroxiredoxin 5;Peroxiredoxin 5;mitochondrial;Peroxiredoxin V;Peroxisomal antioxidant enzyme;PLP;PMP20;PRDX5;Prx V;PRX5;PRXV;SBBI10;Thioredoxin peroxidase PMP20;Thioredoxin reductase;TPx type VI |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC |
| 基因名称 | PRDX5 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of human Peroxiredoxin 5(166-181aa DDSLVSIFGNRRLKRF),identical to the related mouse and rat sequences. |
| 实际分子量 | 22KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | PRDX5(peroxiredoxin 5) also known as AOEB166,ACR1,B166,MGC117264,MGC142283,MGC142285,PLP,PMP20,PRDX6,PRXV,SBBI10,is a member of the peroxiredoxin family and may play an antioxidant protective role in various tissues under nonpathologic conditions and during inflammatory processes.The PRDX5 gene is mapped on 11q13.1.PRDX5 displays mitochondrial presequence features and has 3 cysteines implicated in antioxidant activity and a C-terminal SQL peroxisomal targeting sequence.Northern blot analysis revealed ubiquitous expression of a 1.0-kb PRDX5 transcript in tissues and cell lines.Functional analysis showed that PRDX5 has antioxidant activity equivalent to that of CAT.While PRDX5 was localized to fibroblasts in normal tendon,it was localized to fibroblasts and endothelial cells in degenerative tendon.PRDX5 mRNA and protein levels increased at 12hours,and the increase in PRDX5 expression correlated with reduced peroxide levels.PRDX5 plays a protective role against oxidative stress in human cartilage. |
| Uniprot ID | P30044 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | peroxiredoxin 5 |
| 蛋白名全称 | Peroxiredoxin-5,mitochondrial |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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