加入收藏
百奥莱博公司客服电话百奥莱博QQ百奥莱博QQ百奥莱博QQ
百奥莱博公司微信服务号

产品目录

所在位置:所有产品 > 抗体抗原 > 一抗 > PPP3CA抗体
PPP3CA抗体图片
产品货号:
Z24461
中文名称:
PPP3CA抗体
英文名称:
Anti-PPP3CA Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称Anti-PPP3CA Antibody
指标别名Calcineurin A alpha;CALN;CALNA;CALNA1;CAM PRP catalytic subunit;CCN1;CNA;CNA1;PPP2B;PPP3CA
克隆性Polyclonal
检验物种human,mouse,rat
应用范围WB
基因名称PPP3CA
抗体来源Rabbit
抗体类型IgG
免疫原A synthetic peptide corresponding to a sequence at the C-terminus of human Calcineurin A (488-521aa DAMPSDANLNSINKALTSETNGTDSNGSNSSNIQ),different from the related mouse and rat sequences by one amino acid.
实际分子量59KD
成分500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol.
纯化方式Immunogen affinity purified.
浓度500μg/mL
产品形态溶液
保存条件12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing.
背景资料Calcineurin A is also known as PPP3CA.It is mapped to 4q24.Semsarian et al.(1999) and Musaro et al.(1999) independently showed that IGF1stimulates skeletal muscle hypertrophy and a switch to glycolytic metabolism by activating calcineurin A and inducing the nuclear translocation of transcription factor NFATC1.Semsarian et al.(1999) found that hypertrophy was suppressed by the calcineurin inhibitors cyclosporin A or FK506,but not by inhibitors of the MAP kinase or phosphatidylinositol-3-OH kinase pathways.Musaro et al.(1999) showed that expression of a dominant-negative calcineurin mutant also repressed myocyte differentiation and hypertrophy.Musaro et al.(1999) demonstrated that either IGF1 or activated calcineurin induces expression of transcription factor GATA2,which accumulates in a subset of myocyte nuclei,where it associates with calcineurin and a specific dephosphorylated isoform of NFATC1.
Uniprot IDQ08209
推荐配套试剂Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。
基因名全称protein phosphatase 3,catalytic subunit,alpha isozyme
蛋白名全称Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform
推荐稀释比
Western blot(WB) 1:500~2000

相关搜索:PPP3CA抗体PPP3CA多抗Anti-PPP3CA Antibody
首页 |  关于我们 |  联系我们 |  在线咨询 |  网站地图
北京百奥莱博科技有限公司 京ICP备14007103号-3