产品货号：
Z24360
中文名称：
Protein C/PROC抗体
英文名称：
Anti-Protein C/PROC Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Protein C/PROC Antibody |
| 指标别名 | protein C;inactivator of coagulation factors Va and VIIIa;APC;PC1;THPH3;THPH4;PROC |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC,IHC-F,ICC,FCM |
| 基因名称 | PROC |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of human Protein C(446-461aa HGHIRDKEAPQKSWAP). |
| 实际分子量 | 52KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Protein C(PROC),also called PC,is a zymogenic(inactive) protein,the activated form of which plays an important role in regulating blood clotting,inflammation,cell death and maintaining the permeability of blood vessel walls in humans and other animals.The PROC gene is mapped on 2q14.3.The PROC gene contains 8 exons and spans about 11kb by Foster et al.The conversion of protein C to a protease with anticoagulant function by thrombin requires as a cofactor thrombomodulin,an endothelial cell membrane protein.Riewald et al.demonstrated that activated protein C uses the endothelial cell protein C receptor as a coreceptor for cleavage of protease-activated receptor-1 on endothelial cells.Faust et al.demonstrated that the endothelial pathways required for protein C activation are impaired in severe meningococcal sepsis.They stated that improvement in the outcome of children with meningococcal sepsis who were treated with unactivated protein C concentrates had been described in case reports and in 1 uncontrolled series. |
| Uniprot ID | P04070 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | protein C(inactivator of coagulation factors Va and VIIIa) |
| 蛋白名全称 | Vitamin K-dependent protein C |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunohistochemistry in frozen section (IHC-F) 1:50～400 Immunocytochemistry 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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