产品货号：
Z24325
中文名称：
PRAS40/AKT1S1抗体
英文名称：
Anti-PRAS40/AKT1S1 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-PRAS40/AKT1S1 Antibody |
| 指标别名 | AKT1S1;AKTS1;Lobe;PRAS40;Proline rich AKT1 substrate 1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | AKT1S1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | AKT1S1 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human AKT1S1.The immunogen is located within amino acids 190 - 240 of AKT1S1. |
| 计算分子量 | 27kDa |
| 成分 | AKT1S1 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | AKT1S1 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | The Akt signaling pathway contributes to the regulation of apoptosis after a variety of cell death signals.AKT1S1,also known as PRAS40,is a proline-rich substrate of the kinase AKT1 and is thought to play a role in neuroprotection mediated by nerve growth factor (NGF) after transient focal cerebral ischemia (1).AKT1S1 is also a substrate and potential regulator of mammalian target of rapamycin (mTOR),a serine/threonine kinase that regulates cell growth and cell cycle,and a negative regulator of autophagy (2).Treatment with the insulin-like growth factor-1 (IGF1) can indusce the phosphorylation of AKT1S1 via the PI3K/AKT signaling pathway in PC12 cells (3). |
| Uniprot ID | Q96B36 |
| 基因名全称 | AKT1 substrate 1 (proline-rich) |
| 蛋白名全称 | AKT1 substrate 1 (proline-rich) |
| 推荐稀释比 | AKT1S1 antibody can be used for detection of AKT1S1 by Western blot at 1 ～ 2μg/mL.Antibody validated:Western Blot in human samples;Immunohistochemistry in rat samples and Immunofluorescence in rat samples.All other applications and species not yet tested. |
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