产品货号：
Z24323
中文名称：
PRDM16抗体
英文名称：
Anti-PRDM16 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-PRDM16 Antibody |
| 指标别名 | MEL1;LVNC8;PFM13;CMD1LL;KIAA1675;MEL1;PR domain zinc finger protein 16;PR domain-containing protein 16 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | PRDM16 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | PRDM16 antibody was raised against a 17 amino acid synthetic peptide from near the carboxy terminus of human PRDM16.The immunogen is located within amino acids 1120 - 1170 of PRDM16. |
| 计算分子量 | 140kDa |
| 成分 | PRDM16 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | PRDM16 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | PRDM16 antibody can be stored at 4℃ up to one year.Antibodies should not be exposed to prolonged high temperatures. |
| 背景资料 | PRDM16 is a zinc finger transcription factor and contains an N-terminal PR domain.The reciprocal translocation t(1;3)(p36;q21) occurs in a subset of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML).This gene is located near the 1p36.3 breakpoint and has been shown to be specifically expressed in the t(1:3)(p36,q21)-positive MDS/AML.The translocation results in the overexpression of a truncated version of this protein that lacks the PR domain,which may play an important role in the pathogenesis of MDS and AML.Recent studies have shown that PRDM16 normally acts as a Smad3 binding protein that may be important for the development of orofacial structures through modulation of the TGF-beta signaling pathway.Other experiments have indicated that PRDM16 controls a bidirectional cell fate switch between skeletal myoblasts and brown fat cells. |
| Uniprot ID | Q9HAZ2 |
| 基因名全称 | PR domain containing 16 |
| 蛋白名全称 | PR domain containing 16 |
| 推荐稀释比 | PRDM16 antibody can be used for detection of PRDM16 by Western blot at 1μg/mL.Antibody can also be used for immunohistochemistry starting at 2μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples;Immunohistochemistry in human and mouse samples and Immunofluorescence in human and mouse samples.All other applications and species not yet tested. |
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