产品货号：
Z24243
中文名称：
PPM1D抗体
英文名称：
Anti-PPM1D Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-PPM1D Antibody |
| 指标别名 | Protein phosphatase Mg2+/Mn2+ dependent 1D;p53-induced protein phosphatase 1;PP2C-DELTA;Protein phosphatase 1D;WIP1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | PPM1D |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | PPM1D antibody was raised against an 18 amino acid peptide near the carboxy terminus of human PPM1D.The immunogen is located within the last 50 amino acids of PPM1D. |
| 成分 | PPM1D antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | PPM1D antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | Wild-type p53 induced phosphatase 1 (WIP1)/protein phosphatase magnesium-dependent 1 delta (PPM1D),a protein identified in the p53 DNA response pathway,is a member of the PP2C family of serine/threonine protein phosphatases which selectively inactivates p38 MAPK and dephosphorylates the ATM/ATR targets,Chk1 and p53 (1,2).Studies have shown that it is overexpressed in human cancers and is involved in the regulation of multiple DNA damage signaling pathways (2,3).PPM1D deletion results in a reduction of T and B cell function and compromised cell division,rendering cells resistant to becoming cancerous and slowing tumor development (4,5). |
| Uniprot ID | Q8IVR6 |
| 基因名全称 | Protein phosphatase Mg2+/Mn2+ dependent 1D |
| 蛋白名全称 | Protein phosphatase Mg2+/Mn2+ dependent 1D |
| 推荐稀释比 | PPM1D antibody can be used for detection of PPM1D by Western blot at 1 ～ 2μg/mL.Antibody can also be used for immunohistochemistry starting at 5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in mouse samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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