产品货号：
Z24170
中文名称：
PIAS2抗体
英文名称：
Anti-PIAS2 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-PIAS2 Antibody |
| 指标别名 | ARIP3;DAB2 interacting protein;DIP;E3 SUMO protein ligase PIAS2;miz;MIZ1;PIAS NY protein;PIAS2;PIASX;PIASX ALPHA;PIASX BETA;SIZ2;ZMIZ4 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | PIAS2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | PIAS2 antibody was raised against a 18 amino acid synthetic peptide near the amino terminus of human PIAS2.The immunogen is located within amino acids 110 - 160 of PIAS2. |
| 计算分子量 | 68kDa |
| 成分 | PIAS2 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | PIAS2 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | The PIAS (protein inhibitor of activated STAT) proteins play a crucial role as transcriptional coregulators in various cellular pathways,including the STAT,p53 and the steroid hormone signaling pathway.The PIAS protein family includes at least five evolutionarily conserved genes,including PIAS2.The major function of the PIAS proteins is the control of gene transcription and can also act as small ubiquitin-like-modifier (SUMO) E3 ligases.PIAS2 binds specifically to STAT4 following IL-12 stimulation and inhibits STAT4-mediated gene activation in human T cells.PIAS2 is a potent transcriptional activator of Bcl-2,but together with Bcl-6 can suppress the expression of Bcl-2. |
| Uniprot ID | O75928 |
| 基因名全称 | Protein inhibitor of activated STAT,2 |
| 蛋白名全称 | Protein inhibitor of activated STAT,2 |
| 推荐稀释比 | PIAS2 antibody can be used for detection of PIAS2 by Western blot at 1 ～ 2μg/mL.Antibody can also be used for immunohistochemistry starting at 5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in rat samples;Immunohistochemistry in rat samples and Immunofluorescence in rat samples.All other applications and species not yet tested. |
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