产品货号：
Z24164
中文名称：
PICALM抗体
英文名称：
Anti-PICALM Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-PICALM Antibody |
| 指标别名 | phosphatidylinositol binding clathrin assembly protein;CALM;CLTH;LAP;PICALM |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,ICC/IF,FCM,ELISA |
| 基因名称 | PICALM |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human PICALM recombinant protein (Position:M1-M652). |
| 实际分子量 | 71KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Phosphatidylinositol binding clathrin assembly protein,also known as PICALM,is a protein which in humans is encoded by the PICALM gene.It is mapped to 11q14.2.This gene encodes a clathrin assembly protein,which recruits clathrin and adaptor protein complex 2 (AP2) to cell membranes at sites of coated-pit formation and clathrin-vesicle assembly.The protein may be required to determine the amount of membrane to be recycled,possibly by regulating the size of the clathrin cage.The protein is involved in AP2-dependent clathrin-mediated endocytosis at the neuromuscular junction.A chromosomal translocation t(10;11)(p13;q14) leading to the fusion of this gene and the MLLT10 gene is found in acute lymphoblastic leukemia,acute myeloid leukemia and malignant lymphomas.The polymorphisms of this gene are associated with the risk of Alzheimer disease.Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Uniprot ID | Q13492 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | phosphatidylinositol binding clathrin assembly protein |
| 蛋白名全称 | Phosphatidylinositol-binding clathrin assembly protein |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry (IHC) 1:50～400 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells Enzyme linked immunosorbent assay (ELISA) 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
相关搜索：PICALM抗体，PICALM多抗，Anti-PICALM Antibody