产品货号：
Z24121
中文名称：
POLH抗体
英文名称：
Anti-POLH Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-POLH Antibody |
| 指标别名 | DNA polymerase eta;RAD30;RAD30A;XP-V;XPV;POLH |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,ICC/IF,FCM |
| 基因名称 | POLH |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human POLH recombinant protein (Position:A157-R361).Human POLH shares 93.6% amino acid (aa) sequence identity with mouse POLH. |
| 实际分子量 | 78KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | DNA polymerase eta (Pol η),is a protein that in humans is encoded by the POLH gene.This gene encodes a member of the Y family of specialized DNA polymerases.It copies undamaged DNA with a lower fidelity than other DNA-directed polymerases.However,it accurately replicates UV-damaged DNA;when thymine dimers are present,this polymerase inserts the complementary nucleotides in the newly synthesized DNA,thereby bypassing the lesion and suppressing the mutagenic effect of UV-induced DNA damage.This polymerase is thought to be involved in hypermutation during immunoglobulin class switch recombination.Mutations in this gene result in XPV,a variant type of xeroderma pigmentosum.Several transcript variants encoding different isoforms have been found for this gene. |
| Uniprot ID | Q9Y253 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | polymerase (DNA directed),eta |
| 蛋白名全称 | DNA polymerase eta |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 Immunohistochemistry in paraffin section (IHC) 1:100～500 Flow cytometry (FCM) 1～3μg/1×106 cells |
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