产品货号：
Z23969
中文名称：
PD-1/CD279/PDCD1抗体
英文名称：
Anti-PD-1/CD279/PDCD1 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-PD-1/CD279/PDCD1 Antibody |
| 指标别名 | CD279;hPD 1;hPD l;PD 1;PD1;PD-1;PD-1/CD279;PDCD1;programmed cell death 1;Protein PD 1;SLEB2 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | PDCD1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Anti-PD-1 antibody was raised against a peptide corresponding to 16 amino acids near the carboxy terminus of human PD-1.The immunogen is located within amino acids 210-260 of PD-1. |
| 计算分子量 | 32kDa |
| 成分 | PD-1 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | PD-1 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by cognate peptides bound to MHC molecules on antig en-presenting cells (APC).T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC.PD-1 can bind two different but related ligands,PDL-1 and PDL-2.Upon binding to either of these ligands,signals generated by PD-1 inhibit the activation of the immune response in the absence of "danger signals" such as LPS or other molecules associated with bacteria or other pathogens.Evidence for this is seen in PD1-null mice who exhibit hyperactivated immune systems and autoimmune diseases. |
| Uniprot ID | Q15116 |
| 基因名全称 | Programmed cell death 1 |
| 蛋白名全称 | Programmed cell death 1 |
| 推荐稀释比 | WB:1～4μg/mL;IHC:2.5～5μg/mL;IF:20μg/mL.Antibody validated:Western Blot in human,mouse and rat samples;Immunohistochemistry in human samples;Immunofluorescence in human samples.All other applications and species not yet tested. |
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