产品货号：
Z23966
中文名称：
PD-L1/CD274抗体
英文名称：
Anti-PD-L1/CD274 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-PD-L1/CD274 Antibody |
| 指标别名 | B7 H;B7 H1;B7 homolog 1;B7H1;CD274;CD274 molecule;PD L1;PDCD1 ligand 1;PDCD1L1;PDCD1LG1;PDL1;PD-L1;PD-L1/CD274;Programmed death ligand 1 |
| 克隆性 | Polyclonal |
| 检验物种 | mouse |
| 应用范围 | WB,ELISA |
| 基因名称 | CD274 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived mouse PD-L1/Cd274 recombinant protein (Position:E45-H239). |
| 实际分子量 | 40～50KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Programmed death-ligand 1 (PD-L1),also known as CD274 or B7-H1,is a protein that in humans is encoded by the CD274 gene.It is mapped to 9p24.1.PD-L1 is a 40kDa type 1 transmembrane protein that has been speculated to play a major role in suppressing the immune system during particular events such as pregnancy,tissue allografts,autoimmune disease and other disease states such as hepatitis.It has been concluded that upregulation of PD-L1 on tumor MDCs downregulates T-cell immunity and that PD-L1 blockade may represent an approach for cancer immunotherapy.Additionally,PD-L1 can provide positive costimulatory signals for innate and adaptive immunity and for protection against intracellular bacterial infection.What’s more,it has been found that PD1/PDL1 pathway may be a good target for restoring antitumor immunity in ovarian cancer. |
| Uniprot ID | Q9EP73 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot. |
| 基因名全称 | CD274 antigen |
| 蛋白名全称 | Programmed cell death 1 ligand 1 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 ELISA 1:100～1000 |
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