产品货号：
Z23965
中文名称：
PD-L1/CD274抗体
英文名称：
Anti-PD-L1/CD274 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-PD-L1/CD274 Antibody |
| 指标别名 | B7 H;B7 H1;B7 homolog 1;B7H1;CD274;CD274 molecule;PD L1;PDCD1 ligand 1;PDCD1L1;PDCD1LG1;PDL1;PD-L1;PD-L1/CD274;Programmed death ligand 1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC,IF,FCM |
| 基因名称 | CD274 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Anti-PD-L1 antibody was raised against a peptide corresponding to 17 amino acids near the center of human PD-L1 isoform 1.The immunogen is located within amino acids 60 - 110 of PD-L1. |
| 计算分子量 | 33kDa |
| 成分 | PD-L1 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | PD-L1 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | PD-L1 plays a critical role in induction and maintenance of immune tolerance to self.As a ligand for the inhibitory receptor PDCD1/CD279,PD-L1 modulates the activation threshold of T-cells and limits T-cell effector response (1).The PDCD1/CD279-mediated inhibitory pathway is exploited by tumors to attenuate anti-tumor immunity and facilitate tumor survival (2,3).Through a yet unknown activating receptor,it may costimulate T-cell subsets that predominantly produce interleukin-10 (IL10) (4). |
| Uniprot ID | Q9NZQ7 |
| 基因名全称 | CD274 molecule |
| 蛋白名全称 | CD274 molecule |
| 推荐稀释比 | WB:1～2μg/mL;IHC:2.5～5μg/mL;IF:20μg/mL;Flow Cyt:0.5μg/mL.Antibody validated:Western Blot in human and mouse samples;Immunohistochemistry in human and rat samples;Immunofluorescence in human and rat samples and Flow Cytometry in mouse samples.All other applications and species not yet tested. |
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