产品货号：
Z23955
中文名称：
PAWR抗体
英文名称：
Anti-PAWR Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-PAWR Antibody |
| 指标别名 | Par 4;PAR4;PAWR;Prostate apoptosis response 4 protein |
| 克隆性 | Polyclonal |
| 检验物种 | mouse,rat |
| 应用范围 | ICC/IF,WB,IHC,FCM,ELISA |
| 基因名称 | Pawr |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived mouse PAR4/Pawr recombinant protein (Position:T13-R333). |
| 实际分子量 | 45KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | PRKC,apoptosis,WT1,regulator,also known as PAWR or Prostate apoptosis response-4 (Par-4),is a human gene.This gene encodes a tumor suppressor protein that selectively induces apoptosis in cancer cells through intracellular and extracellular mechanisms.The intracellular mechanism involves the inhibition of pro-survival pathways and the activation of Fas-mediated apoptosis,while the extracellular mechanism involves the binding of a secreted form of this protein to glucose regulated protein 78 (GRP78) on the cell surface,which leads to activation of the extrinsic apoptotic pathway.This gene is located on the unstable human chromosomal 12q21 region and is often deleted or mutated different tumors.The encoded protein also plays an important role in the progression of age-related diseases. |
| Uniprot ID | Q925B0 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot. |
| 基因名全称 | PRKC,apoptosis,WT1,regulator |
| 蛋白名全称 | PRKC apoptosis WT1 regulator protein |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry (IHC) 1:50～400 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells Enzyme linked immunosorbent assay (ELISA) 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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