产品货号：
Z23934
中文名称：
POLR3F抗体
英文名称：
Anti-POLR3F Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-POLR3F Antibody |
| 指标别名 | RPC6;RPC39;DNA-directed RNA polymerase III subunit RPC6;DNA-directed RNA polymerase III subunit F;RNA polymerase III subunit C6 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | POLR3F |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | POLR3F antibody was raised against a 21 amino acid synthetic peptide from near the amino terminus of human POLR3F.The immunogen is located within the first 50 amino acids of POLR3F. |
| 计算分子量 | 36kDa |
| 成分 | POLR3F Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | POLR3F Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | The human POLR3F is a component of RNA III polymerase.RNA polymerase III transcribes many essential,small,noncoding RNAs,including the 5S rRNAs and tRNAs.While most pol III-transcribed genes are found scattered throughout the linear chromosome maps or in multiple linear clusters,there is increasing evidence that many of these genes prefer to be spatially clustered,often at or near the nucleolus.This association could create an environment that fosters the coregulation of transcription by pol III with transcription of the large ribosomal RNA repeats by RNA polymerase I (pol I) within the nucleolus.Given the high number of pol III-transcribed genes in all eukaryotic genomes,the spatial organization of these genes is likely to affect a large portion of the other genes in a genome.POLR3F has also been recently identified as an HIV dependency factor (HDF),suggesting that POLR3F may be an important drug target in HIV treatment.At least two isoforms of POLR3F are known to exist. |
| Uniprot ID | Q9H1D9 |
| 基因名全称 | Polymerase (RNA) III (DNA directed) polypeptide F,39kDa |
| 蛋白名全称 | Polymerase (RNA) III (DNA directed) polypeptide F,39kDa |
| 推荐稀释比 | POLR3F antibody can be used for detection of POLR3F by Western blot at 0.5 ～ 1μg/mL.Antibody can also be used for immunohistochemistry starting at 2.5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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