产品货号：
Z23884
中文名称：
PML抗体
英文名称：
Anti-PML Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-PML Antibody |
| 指标别名 | MYL;PML;PP8675;promyelocytic leukemia;RING finger protein 71;RNF71;TRIM19 |
| 克隆性 | Polyclonal |
| 检验物种 | mouse,rat |
| 应用范围 | WB,IHC,FCM,ELISA |
| 基因名称 | PML |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived mouse Pml recombinant protein (Position:E107-A857). |
| 实际分子量 | 48～160KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | The protein encoded by this gene is a member of the tripartite motif (TRIM) family.The TRIM motif includes three zinc-binding domains,a RING,a B-box type 1 and a B-box type 2,and a coiled-coil region.This phosphoprotein localizes to nuclear bodies where it functions as a transcription factor and tumor suppressor.Its expression is cell-cycle related and it regulates the p53 response to oncogenic signals.The gene is often involved in the translocation with the retinoic acid receptor alpha gene associated with acute promyelocytic leukemia (APL).Extensive alternative splicing of this gene results in several variations of the protein's central and C-terminal regions;all variants encode the same N-terminus.Alternatively spliced transcript variants encoding different isoforms have been identified. |
| Uniprot ID | Q60953 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot. |
| 基因名全称 | promyelocytic leukemia |
| 蛋白名全称 | Protein PML |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section IHC 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells ELISA 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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