产品货号：
Z23851
中文名称：
PKC Gamma/PRKCG抗体
英文名称：
Anti-PKC Gamma/PRKCG Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-PKC Gamma/PRKCG Antibody |
| 指标别名 | PKC gamma;PKCC;PKCG;PRKCG;Protein kinase C gamma type;protein kinase C;gamma;SCA14 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,IF,ICC/IF |
| 基因名称 | PRKCG |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence of human PKC gamma/PRKCG(DRLVLASIDQADFQGFTYVNPDFVHPDARS). |
| 实际分子量 | 80KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | The gamma isotype of protein kinase C (PKC gamma) is a member of the classical PKC (cPKC) subfamily which is activated by Ca(2+) and diacylglycerol in the presence of phosphatidylserine.Physiologically,PKC gamma is activated by a mechanism coupled with receptor-mediated breakdown of inositol phospholipid as other cPKC isotypes such as PKC alpha and PKC beta.PKC gamma is expressed solely in the brain and spinal cord and its localization is restricted to neurons,while PKC alpha and PKC beta are expressed in many tissues in addition to the brain.Within the brain,PKC gamma is the most abundant in the cerebellum,hippocampus and cerebral cortex,where the existence of neuronal plasticity has been demonstrated.PKC gamma gene is mutated in spinocerebellar ataxia type 14 (SCA14).Verbeek et al.(2005) point out the specific alterations in mutant PKC gamma function that could lead to the selective neuronal degeneration of SCA14. |
| Uniprot ID | P05129 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 Immunofluorescence (IF) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
相关搜索：PKC Gamma/PRKCG抗体，PKC Gamma抗体，PRKCG多抗，Anti-PKC Gamma/PRKCG Antibody