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所在位置:所有产品 > 抗体抗原 > 一抗 > PMS2抗体
PMS2抗体图片
产品货号:
Z23743
中文名称:
PMS2抗体
英文名称:
Anti-PMS2 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称Anti-PMS2 Antibody
指标别名PMS1 homolog 2;mismatch repair system component;HNPCC4;MLH4;MMRCS4CL;PMSL2;PMS2;Pms2
克隆性Polyclonal
检验物种mouse,rat
应用范围WB,ELISA
基因名称Pms2
抗体来源Rabbit
抗体类型IgG
免疫原E.coli-derived rat PMS2 recombinant protein (Position:K21-S612).
实际分子量120KD
成分500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol.
纯化方式Immunogen affinity purified.
浓度500μg/mL
产品形态溶液
保存条件12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing.
背景资料Mismatch repair endonuclease PMS2 is an enzyme that in humans is encoded by the PMS2 gene.The protein encoded by this gene is a key component of the mismatch repair system that functions to correct DNA mismatches and small insertions and deletions that can occur during DNA replication and homologous recombination.This protein forms heterodimers with the gene product of the mutL homolog 1 (MLH1) gene to form the MutL-alpha heterodimer.The MutL-alpha heterodimer possesses an endonucleolytic activity that is activated following recognition of mismatches and insertion/deletion loops by the MutS-alpha and MutS-beta heterodimers,and is necessary for removal of the mismatched DNA.There is a DQHA(X)2E(X)4E motif found at the C-terminus of the protein encoded by this gene that forms part of the active site of the nuclease.Mutations in this gene have been associated with hereditary nonpolyposis colorectal cancer (HNPCC;also known as Lynch syndrome) and Turcot syndrome.
Uniprot IDB1H246
推荐配套试剂Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。
基因名全称PMS1 homolog2,mismatch repair system component
蛋白名全称PMS1 homolog 2,mismatch repair system component
推荐稀释比
Western blot(WB) 1:500~2000
(ELISA): 1:100~1000

相关搜索:PMS2抗体PMS2多抗Anti-PMS2 Antibody
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