产品货号：
Z23434
中文名称：
PCGF1抗体
英文名称：
Anti-PCGF1 Antibody (Center)
产品规格：
80μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-PCGF1 Antibody (Center) |
| 指标别名 | Polycomb group RING finger protein 1,Nervous system Polycomb-1,NSPc1,RING finger protein 68,PCGF1,NSPC1,RNF68 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB |
| 基因名称 | PCGF1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | This PCGF1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 117-151 amino acids from the Central region of human PCGF1. |
| 计算分子量 | 30kDa |
| 成分 | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
| 纯化方式 | This antibody is purified through a protein A column,followed by peptide affinity purification |
| 保存条件 | Maintain refrigerated at 2～8℃ for up to 2 weeks.For long term storage,store at -20℃ in small aliquots to prevent freeze-thaw cycles. |
| 背景资料 | Component of the Polycomb group (PcG) multiprotein BCOR complex,a complex required to maintain the transcriptionally repressive state of some genes,such as BCL6 and the cyclin- dependent kinase inhibitor,CDKN1A.Transcriptional repressor that may be targeted to the DNA by BCL6;this transcription repressor activity may be related to PKC signaling pathway.Represses CDKN1A expression by binding to its promoter,and this repression is dependent on the retinoic acid response element (RARE element).Promotes cell cycle progression and enhances cell proliferation as well.May have a positive role in tumor cell growth by down- regulating CDKN1A.Component of a Polycomb group (PcG) multiprotein PRC1-like complex,a complex class required to maintain the transcriptionally repressive state of many genes,including Hox genes,throughout development.PcG PRC1 complex acts via chromatin remodeling and modification of histones;it mediates monoubiquitination of histone H2A 'Lys-119',rendering chromatin heritably changed in its expressibility. |
| Uniprot ID | Q9BSM1 |
相关搜索：PCGF1抗体，PCGF1(Center)多抗，Anti-PCGF1 Antibody (Center)