产品货号:
Z23421
中文名称:
PAR2/F2RL1抗体
英文名称:
Anti-PAR2/F2RL1 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
| 抗体名称 | Anti-PAR2/F2RL1 Antibody |
| 指标别名 | F2RL1;G protein coupled receptor 11;GPR11;PAR 2;PAR2;Thrombin receptor like 1 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB |
| 基因名称 | F2RL1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of human PAR2 (349-383aa HDFRDHAKNALLCRSVRTVKQMQVSLTSKKHSRKS),different from the related mouse sequence by eight amino acids,and from the related rat sequence by seven amino acids. |
| 实际分子量 | 49KD |
| 成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Protease activated receptor 2 (PAR2),also known as°Coagulation factor II (thrombin) receptor-like 1(F2RL1) or G-protein coupled receptor 11 (GPR11),is a protein that in humans is encoded by the F2RL1 gene.F2RL1 is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins.F2RL1 is also a member of the protease-activated receptor family.It is activated by trypsin,but not by thrombin.It is activated by proteolytic cleavage of its extracellular amino terminus.The new amino terminus functions as a tethered ligand and activates the receptor.The F2RL1 gene contains two exons and is widely expressed in human tissues.Additionally,PAR2 modulates inflammatory responses and acts as a sensor for proteolytic enzymes generated during infection. |
| Uniprot ID | P55085 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | coagulation factor II (thrombin) receptor-like 1 |
| 蛋白名全称 | Proteinase-activated receptor 2 |
| 推荐稀释比 | Western blot(WB) 1:500~2000 |
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