产品货号：
Z23420
中文名称：
PAPPA抗体
英文名称：
Anti-PAPPA Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-PAPPA Antibody |
| 指标别名 | pappalysin 1;ASBABP2;DIPLA1;IGFBP-4ase;PAPA;PAPP-A1;PAPPA |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC |
| 基因名称 | PAPPA |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human PAPP A recombinant protein (Position:R95-Q388).Human PAPP A shares 88% amino acid (aa) sequence identity with mouse PAPP A. |
| 实际分子量 | 181KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Pappalysin-1,also known as DIPLA1,is a protein that in humans is encoded by the PAPPA gene.It is mapped to 9q33.1.PAPPA is found in the ovarian follicles,follicular fluid,luteal cells,and fallopian tubes of nonpregnant women and in the seminal vesicles and seminal fluid of males.This gene encodes a secreted metalloproteinase which cleaves insulin-like growth factor binding proteins (IGFBPs).It is thought to be involved in local proliferative processes such as wound healing and bone remodeling.Low plasma level of this protein has been suggested as a biochemical marker for pregnancies with aneuploid fetuses.It has been found that circulating PAPPA is a disulfide-bridged complex with proMBP in which the subunits of the constituents are present in a 1:1 molar ratio. |
| Uniprot ID | Q13219 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | pregnancy-associated plasma protein A,pappalysin 1 |
| 蛋白名全称 | Pappalysin-1 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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