产品货号：
Z23409
中文名称：
PARC/CUL9抗体
英文名称：
Anti-PARC/CUL9 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-PARC/CUL9 Antibody |
| 指标别名 | PARC;p53 associated parkin like cytoplasmic protein;RP3 330M21.2;UbcH 7 associated protein 1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | ELISA,WB,ICC,IF |
| 基因名称 | CUL9 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | PARC antibody was raised against a 17 amino acid synthetic peptide from near the carboxy terminus of human PARC.The immunogen is located within the last 50 amino acids of PARC. |
| 计算分子量 | 281kDa |
| 成分 | PARC Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | PARC Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | The continued localization of p53 to the nucleus is essential for its function as a tumor suppressor.PARC,a large,Parkin-like ubiquitin ligase has recently been identified as a cytoplasmic anchor protein in p53-associated protein complexes.In the absence of stress,PARC inactivation results in nuclear localization of p53 and activation of p53-dependent apoptosis,while overexpression of this protein promoted cytoplasmic sequestration of p53.Surprisingly,PARC knockout mice were viable and exhibited no obvious phenotype,suggesting that other proteins,such as the highly related cullin family of E3 ubiquitin ligases,may perform similar functions in the absence of PARC.Additionally,it has been suggested that p53 binding to PARC may serve to control PARC function. |
| Uniprot ID | Q8IWT3 |
| 基因名全称 | Cullin 9 |
| 蛋白名全称 | Cullin 9 |
| 推荐稀释比 | PARC antibody can be used for the detection of PARC by Western blot at 1 ～ 2μg/mL.Antibody can also be used for immunocytochemistry starting at 1μg/mL.For immunofluorescence start at 2μg/mL.Antibody validated:Western Blot in human samples;Immunocytochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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