产品货号：
Z23369
中文名称：
p53R2/RRM2B抗体
英文名称：
Anti-p53R2/RRM2B Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-p53R2/RRM2B Antibody |
| 指标别名 | p53R2;RRM2B;RRM2B;p53R2 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | RRM2B |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | p53R2 antibody was raised against a 16 amino acid peptide near the amino terminus of human p53R2.The immunogen is located within the first 50 amino acids of p53R2. |
| 计算分子量 | 41kDa |
| 成分 | p53R2 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | p53R2 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | The p53 tumor-suppressor gene integrates numerous signals that control cell life and death.Several novel molecules involved in p53 signaling,including p53R2,Chk2,p53AIP1,Noxa,PIDD,and PID/MTA2,were recently discovered.p53R2 is a p53 inducible gene that contains a p53 binding sequence and encodes a subunit of the enzyme ribonucleotide reductase.p53R2 is induced by the reagents,ultraviolet and gamma-irradiation that cause DNA damages.The product of p53R2 gene is directly involved in the p53 checkpoint for repair of damaged DNA.The isoform of the p53 family member p73 also induces p53R2 expression.p53R2 is an important target of p53 for tumor suppression. |
| Uniprot ID | Q7LG56 |
| 基因名全称 | Ribonucleotide reductase M2 B (TP53 inducible) |
| 蛋白名全称 | Ribonucleotide reductase M2 B (TP53 inducible) |
| 推荐稀释比 | p53R2 antibody can be used for detection of p53R2 by Western blot at 1μg/mL.Antibody can also be used for immunohistochemistry starting at 1μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in mouse samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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