产品货号：
Z23325
中文名称：
P glycoprotein/ABCB1抗体
英文名称：
Anti-P glycoprotein/ABCB1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-P glycoprotein/ABCB1 Antibody |
| 指标别名 | ABCB1;CD243;GP170;MDR1;Multidrug resistance protein 1;P glycoprotein;P glycoprotein 1;P-gp |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,FCM,ELISA |
| 基因名称 | ABCB1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human P Glycoprotein/ABCB1 recombinant protein (Position:R669-Y710). |
| 实际分子量 | 130～180KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | P-GP,also called ABCB1 or PGY1,is a glycoprotein that in humans is encoded by the ABCB1 gene.It is mapped to 7q21.12.P-GP is a well-characterized ABC-transporter (which transports a wide variety of substrates across extra- and intracellular membranes) of the MDR/TAP subfamily.It is an important protein of the cell membrane that pumps many foreign substances out of cells.More formally,it is an ATP-dependent drug efflux pump with broad substrate specificity.P-GP is an ATP-dependent drug efflux pump forxenobiotic compounds with broad substrate specificity.It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs.This protein also functions as a transporter in the blood–brain barrier. |
| Uniprot ID | P08183 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot. |
| 基因名全称 | ATP-binding cassette,sub-family B (MDR/TAP),member 1 |
| 蛋白名全称 | Multidrug resistance protein 1 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section IHC 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells ELISA： 1:100～1000 |
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