产品货号：
Z23224
中文名称：
p75NTR/NGFR抗体
英文名称：
Anti-p75NTR/NGFR Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-p75NTR/NGFR Antibody |
| 指标别名 | CD271;Gp80 LNGFR;NGF receptor;NGFR;p75;p75 ICD;p75(NTR);p75NTR;TNFRSF16 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | ELISA,WB,ICC,IF |
| 基因名称 | NGFR |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | NGFR antibody was raised against purified recombinant human NGFR. |
| 计算分子量 | 45kDa |
| 成分 | NGFR Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | NGFR Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | The tumor necrosis factor (TNF) and TNF receptor (TNFR) gene superfamilies regulate numerous biological functions including cell proliferation,differentiation,and survival through regulating the activation of the transcription factor NF-百B and various mitogen-activated protein kinases.Nerve growth factor receptor (NGFR) was one of the earliest characterized members of this family.Also known as the low-affinity receptor p75NTR,this receptor is involved in several diverse functions such as apoptosis,neurite outgrowth during development,and myelination.Its ligands include NGF,brain-derived neurotrophic factor (BDNF),NT3,and NT4.NGFR can also associate with other NGF receptors such as Trk through the cytosolic and transmembrane domains and thus can function as a co-receptor that refines Trk affinity and specificity for neurotrophins.Finally,upon binding of various neurotrophins,NGFR associates with tumor necrosis factor receptor-6 (TRAF6),suggesting that it can potentially function as a signal transducer for NGF signals through NGFR. |
| Uniprot ID | P08138 |
| 基因名全称 | Nerve growth factor receptor (TNFR superfamily,member 16) |
| 蛋白名全称 | Nerve growth factor receptor (TNFR superfamily,member 16) |
| 推荐稀释比 | NGFR antibody can be used for the detection of NGFR by Western blot at 1μg/mL.Antibody can also be used for immunocytochemistry starting at 10μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples,Immunocytochemistry in mouse samples and Immunofluorescence in human samples..All other applications and species not yet tested. |
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