产品货号：
Z23218
中文名称：
PAGR1抗体
英文名称：
Anti-PAGR1 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-PAGR1 Antibody |
| 指标别名 | GAS;PA1;C16orf53;PAXIP1-associated glutamate-rich protein 1;PAXIP1-associated protein 1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | ELISA,WB |
| 基因名称 | PAGR1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | GAS antibody was raised against a 15 amino acid synthetic peptide from near the carboxy terminus of human GAS.The immunogen is located within the last 50 amino acids of GAS. |
| 计算分子量 | 28kDa |
| 成分 | GAS Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | GAS Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | Steroid receptor co-activators (SRCs) were initially described as nuclear receptor transcription co-activators,but they have recently been determined to co-regulate transcription initiated by other transcription factors.GAS is a recently identified glutamate-rich protein that interacts with SRC1,but not GRIP1 or AIB1,the other two members of the SRC family.GAS can also interact with the alpha subunit of the estrogen receptor (ERalpha),but not other receptors such as the retinoic acid receptor a,suggesting the interaction between GAS and ERalpha is relatively specific.Depletion of GAS by RNA interference in MCF7 cells led to a decrease in the mRNA and protein levels of ER target genes such as pS2,c-Myc and cyclin D1,indicating the role of GAS in the regulation of ER target genes.GAS has also been found to associate with an SET1-like methyltransferase complex specific for H3K4 methylation,suggesting that GAS has multiple roles in transcriptional regulation. |
| Uniprot ID | Q9BTK6 |
| 基因名全称 | PAXIP1 associated glutamate rich protein 1 |
| 蛋白名全称 | PAXIP1 associated glutamate rich protein 1 |
| 推荐稀释比 | GAS antibody can be used for detection of GAS by Western blot at 1μg/mL.Antibody validated:Western Blot in mouse samples.All other applications and species not yet tested. |
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