产品货号:
Z23181
中文名称:
PINX1抗体
英文名称:
Anti-PINX1 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-PINX1 Antibody |
指标别名 | LPTL;LPTS;PIN2 interacting protein 1;Pin2 interacting protein X1;PINX1;Protein 67 11 3;TRF1 interacting protein 1 |
克隆性 | Polyclonal |
检验物种 | human |
应用范围 | WB |
基因名称 | PINX1 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | A synthetic peptide corresponding to a sequence at the N-terminus of human PINX1 (54-83aa DHIKVQVKNNHLGLGATINNEDNWIAHQDD),different from the related mouse and rat sequences by three amino acids. |
实际分子量 | 37KD |
成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
纯化方式 | Immunogen affinity purified. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | PINX1,also known as PIN2 interacting protein 1,is a telomerase inhibitor and a possible tumor suppressor.It is mapped to 8p23.Over-expression of PINX1 results in decreased telomerase activity,telomere shortening,and induction of crisis.Reduction of PINX1 leads to an increase in telomerase activity and elongation of telomeres.PINX1 differs from other proteins that regulate telomere length in that it acts on telomerase while other proteins adjust telomere length without affecting telomerase activity.The PINX1 budding yeast orthologue Gnop1 inhibits telomerase by isolating the uncomplexed TERT protein so that it cannot associate with the telomerase template RNA,which prevents telomerase from being assembled.However,in humans,PINX1 impedes already assembled telomerase. |
Uniprot ID | Q96BK5 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
基因名全称 | PIN2/TERF1 interacting,telomerase inhibitor 1 |
蛋白名全称 | PIN2/TERF1-interacting telomerase inhibitor 1 |
推荐稀释比 | Western blot(WB) 1:500~2000 |
相关搜索:PINX1抗体,PINX1多抗,Anti-PINX1 Antibody