产品货号：
Z23165
中文名称：
PIN1抗体
英文名称：
Anti-PIN1 Antibody
产品规格：
100μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-PIN1 Antibody |
| 指标别名 | DOD;PIN1;PPIase Pin1;Rotamase Pin1;UBL5 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | IHC,IF,ELISA |
| 基因名称 | PIN1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Synthesized peptide derived from human Pin1 around the non-phosphorylation site of S16. |
| 计算分子量 | 18KD |
| 成分 | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| 纯化方式 | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | -20℃可保存1年，短期保存或频繁使用请置于4℃，可保存一个月，避免反复冻融。 |
| 背景资料 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1,also called DOD,is an enzyme that in humans is encoded by the PIN1 gene.It is mapped to 19p13.2.The enzyme binds to a subset of proteins and thus plays a role as a post phospho PIN1rol in regulating protein function.Studies have shown that the deregulation of PIN1 may play a pivotal role in various diseases.Notably,the up-regulation of PIN1 may be implicated in certain cancers,and the down-regulation of Pin1 may be implicated in Alzheimer's disease.Inhibitors of PIN1 may have therapeutic implications for cancer and immune disorders.PIN1 activity regulates the outcome of proline-directed kinase (e.g.MAPK,CDK or GSK3) signalling and consequently regulates cell proliferation (in part through control of cyclin D1 levels and stability) and cell survival.PIN1 also has an essential role in maintaining cell proliferation and regulating cyclin D1 function. |
| Uniprot ID | Q13526 |
| 基因名全称 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 |
| 蛋白名全称 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 |
| 推荐稀释比 | IHC 1:100～1:300 IF 1:200～1:1000 ELISA 1:5000 |
相关搜索：PIN1抗体，PIN1多抗，Anti-PIN1 Antibody