产品货号:
Z23162
中文名称:
PINK1抗体
英文名称:
Anti-PINK1 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-PINK1 Antibody |
指标别名 | BRPK;PARK6;PINK1;PTEN induced putative kinase 1 |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | ELISA,WB,IHC,IF |
基因名称 | PINK1 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | PINK1 antibody was raised against a 16 amino acid peptide near the amino terminus of human PINK1.The immunogen is located within amino acids 120 - 170 of PINK1. |
计算分子量 | 63kDa |
成分 | PINK1 antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | PINK1 antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | The PTEN-induced putative kinase 1 (PINK1) is a serine/threonine protein kinase that localizes to mitochondria and is thought to protect cells from stress-induced mitochondrial dysfunction (reviewed in 1).PINK1 recruits the E3 ubiquitin ligase Parkin to mitochondria to initiate mitophagy,an autophagic process that clears damaged mitochondria within a cell (2).PINK1 is cleaved by the mitochondrial protease PARL (3).Mutations in this gene cause one form of autosomal recessive early-onset Parkinson disease (4). |
Uniprot ID | Q9BXM7 |
基因名全称 | PTEN induced putative kinase 1 |
蛋白名全称 | PTEN induced putative kinase 1 |
推荐稀释比 | PINK1 antibody can be used for detection of PINK1 by Western blot at 1 ~ 2μg/mL.Antibody can also be used for immunohistochemistry starting at 5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human,mouse,and rat samples;Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples.All other applications and species not yet tested. |
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