产品货号：
Z23072
中文名称：
OTUD5抗体
英文名称：
Anti-OTUD5 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-OTUD5 Antibody |
| 指标别名 | DUBA;OTU domain-containing protein 5;Deubiquitinating enzyme A;DUBA |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | OTUD5 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | OTUD5 antibody was raised against a 13 amino acid synthetic peptide near the carboxy terminus of the human OTUD5.The immunogen is located within amino acids 400 - 450 of OTUD5. |
| 计算分子量 | 61kDa |
| 成分 | OTUD5 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | OTUD5 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | OTUD5 is a member of the OTU (ovarian tumor) domain-containing cysteine protease superfamily.The OTU domain confers deubiquitinase activity and OTUD5 has been shown to suppress the type I interferon (IFN-I)-dependent innate immune response by cleaving the polyubiquitin chain from TRAF3,an essential type I interferon adaptor protein.Cleavage results in disassociation of TRAF3 from a downstream signaling complex containing TBK1 and the disruption of the IFN-I signaling cascade,indicating that OTUD5 acts as a negative regulator of innate immune responses.It has been suggested that by suppressing IFN-I production,OTUD5 may function to inhibit the emergence of certain autoimmune disorders such as systemic lupus erythematosus.Multiple isoforms of OTUD5 are known to exist. |
| Uniprot ID | Q96G74 |
| 基因名全称 | OTU domain containing 5 |
| 蛋白名全称 | OTU domain containing 5 |
| 推荐稀释比 | OTUD5 antibody can be used for detection of OTUD5 by Western blot at 1 ～ 2μg/mL.Antibody can also be used for immunohistochemistry starting at 2.5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples;Immunohistochemistry in mouse samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
相关搜索：OTUD5抗体，OTUD5多抗，Anti-OTUD5 Antibody