产品货号：
Z23041
中文名称：
PDGFR alpha/PDGFRA抗体
英文名称：
Anti-PDGFR alpha/PDGFRA Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-PDGFR alpha/PDGFRA Antibody |
| 指标别名 | platelet derived growth factor receptor alpha;CD140A;PDGFR-2;PDGFR2;PDGFRA |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC |
| 基因名称 | PDGFRA |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of human PDGFRA (968-1002aa DFLKSDHPAVARMRVDSDNAYIGVTYKNEEDKLKD),identical to the related mouse sequence,and different from the related rat sequence by one amino acid. |
| 实际分子量 | 180KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | PDGFRA (Platelet-derived growth factor receptor,alpha),also called PDGFR2,encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family.The PDGFA gene is mapped on 4q12.The PDGFRA-FIP1L1 gene is a constitutively activated tyrosine kinase that transforms hematopoietic cells and is a therapeutic target of imatinib.And the PDGFRA gene contains 23 exons spanning about 65kb.Using the human PDGFRA promoter linked to a luciferase reporter,Joosten et al.showed that PAX1 acts as a transcriptional activator of the PDGFRA gene in differentiated human embryonal carcinoma cells.PDGFRA is responsible for mediating cellular contraction of multiple growth factors:TGFB1 and members of the PDGF family.Lei et al.noted that in the rabbit model of the disease,PDGFRA is dramatically more capable of promoting PVR than is the closely related PDGFRB.PDGFRA is a critical receptor required for human CMV infection,and thus a target for novel antiviral therapies. |
| Uniprot ID | P16234 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | platelet-derived growth factor receptor,alpha polypeptide |
| 蛋白名全称 | Platelet-derived growth factor receptor alpha |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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