产品货号：
Z22954
中文名称：
PARL抗体
英文名称：
Anti-PARL Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-PARL Antibody |
| 指标别名 | MAMP,PACT,PARL,Pbeta,PRO2207,PSARL,PSARL1,PSENIP2,RHBDS1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,ICC,IF |
| 基因名称 | PARL |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | PARL antibody was raised against a 15 amino acid synthetic peptide from near the amino terminus of human PARL.The immunogen is located within amino acids 40 - 90 of PARL. |
| 计算分子量 | 42kDa |
| 成分 | PARL Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | PARL Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | PARL is a mitochondrial integral membrane protein and a member of the highly conserved rhomboid superfamily of membrane proteins.PARL is required for the control of apoptosis during postnatal growth and is required for the processing of OPA1,a protein that prevents the release of cytochrome C from the mitochondria in response to apoptotic signals.In lymphocytes and neurons,PARL's association with other proteins,such as the Bcl-2 family-related protein Hax1 and Omi can lead to the proteolytic processing of Omi by PARL,preventing the accumulation of Bax,thereby suppressing apoptosis.Variations in this gene have been associated with increased risk for type 2 diabetes.PARL may also play a role in the progression of Alzheimer's disease through its associations with presenilin-1 and -2.Multiple isoforms of PARL are known to exist. |
| Uniprot ID | Q9H300 |
| 基因名全称 | Presenilin associated,rhomboid-like |
| 蛋白名全称 | Presenilin associated,rhomboid-like |
| 推荐稀释比 | PARL antibody can be used for detection of PARL by Western blot at 1 ～ 2μg/mL.Despite its predicted molecular weight of~42kDa,PARL is observed at a higher molecular weight in SDS-PAGE.Antibody can also be used for immunocytochemistry starting at 2.5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in mouse samples;Immunocytochemistry in mouse samples and Immunofluorescence in mouse samples.All other applications and species not yet tested. |
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