产品货号：
Z22941
中文名称：
PAK5/PAK7抗体
英文名称：
Anti-PAK5/PAK7 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-PAK5/PAK7 Antibody |
| 指标别名 | KIAA1264;p21 activated kinase 5;p21 activated kinase 7;PAK 5;PAK 7;PAK5;PAK7 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC |
| 基因名称 | PAK7 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the N-terminus of human PAK5 (26-55aa DPQEQKFTGLPQQWHSLLADTANRPKPMVD),identical to the related mouse and rat sequences. |
| 实际分子量 | 81KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Serine/threonine-protein kinase PAK 7,also known as PAK5,is an enzyme that in humans is encoded by the PAK7 gene.The protein encoded by this gene is a member of the PAK family of Ser/Thr protein kinases.PAK family members are known to be effectors of Rac/Cdc42 GTPases,which have been implicated in the regulation of cytoskeletal dynamics,proliferation,and cell survival signaling.This kinase contains a CDC42/Rac1 interactive binding (CRIB) motif,and has been shown to bind CDC42 in the presence of GTP.And this kinase is predominantly expressed in brain.It is capable of promoting neurite outgrowth,and thus may play a role in neurite development.In addition,this kinase is associated with microtubule networks and induces microtubule stabilization.The subcellular localization of this kinase is tightly regulated during cell cycle progression.Alternatively spliced transcript variants encoding the same protein have been described. |
| Uniprot ID | Q9P286 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | p21 protein (Cdc42/Rac)-activated kinase 7 |
| 蛋白名全称 | Serine/threonine-protein kinase PAK 7 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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