产品货号：
Z22820
中文名称：
P-Cadherin/CDH3抗体
英文名称：
Anti-P-Cadherin/CDH3 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-P-Cadherin/CDH3 Antibody |
| 指标别名 | Cadherin 3;CDH3;CDHP;HJMD;PCAD;P-cadherin |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC,ICC |
| 基因名称 | CDH3 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence in the middle region of human P cadherin(612-626aa QDTYDVHLSLSDHGN),different from the mouse and rat sequences by one amino acid. |
| 实际分子量 | 120KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Cadherins,such as CDH3,are integral membrane glycoproteins responsible for calcium-dependent cell-cell adhesion.Cadherin-3 is a protein that in humans is encoded by the CDH3 gene.This gene is a classical cadherin from the cadherin superfamily.The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein composed of five extracellular cadherin repeats,a transmembrane region and a highly conserved cytoplasmic tail.This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer.In addition,aberrant expression of this protein is observed in cervical adenocarcinomas.Mutations in this gene have been associated with congential hypotrichosis with juvenile macular dystrophy. |
| Uniprot ID | P22223 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | cadherin 3,type 1,P-cadherin(placental) |
| 蛋白名全称 | Cadherin-3 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunocytochemistry 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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