产品货号:
Z22808
中文名称:
P0/MPZ抗体
英文名称:
Anti-P0/MPZ Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
| 抗体名称 | Anti-P0/MPZ Antibody |
| 指标别名 | CHM,CMT1,CMT1B,CMT2I,CMT2J,CMT4E,CMTDI3,DSS,HMSNIB,MPP,MPZ,MPZ/P0,Myelin peripheral protein,Myelin protein P0,myelin protein zero,P0 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,ELISA |
| 基因名称 | MPZ |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human Myelin Protein Zero recombinant protein (Position:I30-R153). |
| 实际分子量 | 28KD |
| 成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Myelin protein zero (P0,MPZ) is a glycoprotein which in humans is encoded by the MPZ gene.This gene is specifically expressed in Schwann cells of the peripheral nervous system and encodes a type I transmembrane glycoprotein that is a major structural protein of the peripheral myelin sheath.The encoded protein contains a large hydrophobic extracellular domain and a smaller basic intracellular domain,which are essential for the formation and stabilization of the multilamellar structure of the compact myelin.Mutations in this gene are associated with autosomal dominant form of Charcot-Marie-Tooth disease type 1 (CMT1B) and other polyneuropathies,such as Dejerine-Sottas syndrome (DSS) and congenital hypomyelinating neuropathy (CHN).A recent study showed that two isoforms are produced from the same mRNA by use of alternative in-frame translation termination codons via a stop codon readthrough mechanism. |
| Uniprot ID | P25189 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 推荐稀释比 | Western blot(WB) 1:500~2000 (ELISA): 1:100~1000 |
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